Clinical trials are very important for development of drugs, vaccines and devices. As individuals varies in genetic make-up, social and environmental factors, a diverse and adequate representation of various population in the clinical trials is crucial to make policy and treatment guideline decisions. Africa comprises 54 countries and around 1.5 billion people live in the continent, which constitutes the world 17% of the population. The population in Africa is genetically very diverse and the continent carries 20% of the global disease burden with both communicable and non-communicable diseases (1). However, the continent is less represented in clinical trials with less than 3% of trials conducted in Africa (2).